Pulmonary parenchymal involvement secondary to subcutaneous injection of silicone gels: a case report.
Horizonte Medico
; 23(1) (no pagination), 2023.
Article
in Spanish
| EMBASE | ID: covidwho-2314435
ABSTRACT
Pulmonary parenchymal involvement secondary to the subcutaneous injection of silicone gels is an unusual condition which occurs more frequently in women aged between 22 and 55 years. Although different theories have been put forward about its etiology, it is unknown and the condition may cause local and systemic complications and even have a fatal outcome. Few cases have been reported in South America and there is no report of this unique entity in Peru. We present the case of a previously healthy 28-year-old male transgender patient who, after an illegal subcutaneous injection of silicone gels in the gluteal region given by a non-healthcare professional, showed progressive respiratory distress and stabbing chest pain of approximately 7 out of 10 on the pain scale within the first 24 hours. Upon admission to the emergency room, respiratory failure was objectively evidenced since the patient had an oxygen saturation of 72 % at a FiO2 of 21 %, as well as pulmonary parenchymal involvement both in the CT scan and chest X-ray with signs highly suggestive of this pathology. Using a SARS-CoV-2 RNA real-time RT-PCR test performed on a respiratory specimen, COVID pneumonia, immunodeficiency disorders and pulmonary embolism were ruled out. Since there is no standard treatment, the patient was given relevant support measures such as the administration of supplemental oxygen at a low flow rate by binasal cannula, intravenous systemic corticosteroids and antibiotic therapy, thus achieving good progress with resolution of the initial clinical presentation. Then, after 10 days of intrahospital treatment, the patient was discharged.Copyright © La revista. Publicado por la Universidad de San Martin de Porres, Peru.
Lung; Respiratory Insufficiency; Silicone Gels (Source: MeSH NLM); adult; antibiotic therapy; article; case report; clinical article; coronavirus disease 2019/di [Diagnosis]; coronavirus disease 2019/dt [Drug Therapy]; coronavirus disease 2019/th [Therapy]; corticosteroid therapy; COVID-19 nucleic acid testing; emergency ward; human; immune deficiency/di [Diagnosis]; immune deficiency/dt [Drug Therapy]; immune deficiency/th [Therapy]; lung embolism/di [Diagnosis]; lung embolism/dt [Drug Therapy]; lung embolism/th [Therapy]; lung parenchyma; male; nasal cannula therapy; oxygen saturation; oxygen therapy; pain assessment; real time reverse transcription polymerase chain reaction; respiratory distress; respiratory failure; Severe acute respiratory syndrome coronavirus 2; subcutaneous drug administration; systemic therapy; thorax pain; thorax radiography; transgender; x-ray computed tomography; antibiotic agent/dt [Drug Therapy]; corticosteroid/dt [Drug Therapy]; corticosteroid/iv [Intravenous Drug Administration]; silicone gel/to [Drug Toxicity]; virus RNA/ec [Endogenous Compound]
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Case report
Language:
Spanish
Journal:
Horizonte Medico
Year:
2023
Document Type:
Article
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