Histomorphological Spectrum of Lung Lesions at Autopsy-A Tertiary Care Centre Experience
JK Science
; 25(2):93-97, 2023.
Article
in English
| EMBASE | ID: covidwho-2315086
ABSTRACT
Background and aims:
A wide variety of pathological conditions involve the lungs. In autopsy, the lungs are examined for disease, injury and other findings suggesting cause of death or related changes.Aims &Objectives:
The present study aimed to study the histomorphological spectrum of lung lesions at autopsy and to assess the frequency of different types of lesions;and to associate histomorphological changes with cause of death.Material andMethods:
It was a one-year observational study conducted in the Department of Pathology, Govt. Medical College, Jammu. Lung tissue pieces from all medicolegal autopsies received were fixed, examined grossly, processed;paraffin embedded sections obtained were stained with Hematoxylin and Eosin stain and examined under microscope. Findings were recorded and tabulated. Result(s) Out of 264 cases, males were predominantly affected (84%);median age was 38 years. The various changes observed were congestion (68%), edema (45.4%), pneumonia (5%), granulomatous inflammation (3%), diffuse alveolar damage (1.5%), haemorrhage (14.4%), interstitial changes (60%), malaria (0.4%) and malignancy (0.4%). Natural deaths were the commonest cause (75, 28%) followed by asphyxial deaths (65, 24.6%). Conclusion(s) Histopathological examination of lung autopsies highlights many incidental findings, establishes underlying cause of death, serves as a learning tool and also holds scope for detection of newer diseases.Copyright © 2023 JK Science.
Autopsy; Histopathology; Lung; adenocarcinoma; adult; adult respiratory distress syndrome; alcohol intoxication; article; asphyxia; bleeding; cause of death; chronic kidney failure; chronic liver disease; coronary artery disease; coronavirus disease 2019; death; diffuse alveolar damage; drug abuse; female; foreign body; granulomatous inflammation; head injury; heat stroke; hemosiderin laden macrophage; human; Human immunodeficiency virus infection; human tissue; interstitial lung disease; lung congestion; lung edema; lung fibrosis; lung lesion; lung parenchyma; malaria; male; malignant neoplasm; microscopy; middle aged; observational study; paraffin embedding; periodic acid Schiff stain; pneumonia; septicemia; staining; sudden cardiac death; tuberculosis; young adult; microscope; Hematoxylin and eosin stain; histomorphology; ziehl neelsen stain
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
JK Science
Year:
2023
Document Type:
Article
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