Neuromyelitis optica spectrum disorder after BIBP COVID-19 vaccine: A case report
Neuroimmunology Reports
; 3 (no pagination), 2023.
Article
in English
| EMBASE | ID: covidwho-2315103
ABSTRACT
Background:
With the COVID-19 vaccine now available, there have been occasional reports of post-vaccination neurological complications. Case presentation In this report, we present a case of neuromyelitis optica spectrum disorder (NMOSD) that developed one month after the patient received the second dose of BIBP COVID-19 vaccine (SARS-CoV-2-Vaccine [Vero Cell] Inactivated). The patient presented with itching, numbness in the hand and right side of the face, as well as nausea, vomiting, and hiccups. Brain MRI revelead lesions in the area postrema, medulla, and bilateral hypothalamus, which are typical of NMOSD. Serum antibodies to anti-AQP4 and anti-MOG were negative. Conclusion(s) The pathogenesis of NMOSD development after vaccination is still unknown. NMOSD is generally aggressive and disabling, it is important for the neurologist to be attentive to the highly variable clinical presentation after COVID-19 vaccination for early diagnosis and effective treatment.Copyright © 2023
COVID-19 vaccines; Neuromyelitis optica; SARS-CoV-2; Vaccination; adult; antibody blood level; area postrema; article; case report; clinical article; coronavirus disease 2019; diagnosis; drug therapy; drug toxicity; early diagnosis; female; hand paresthesia; hiccup; human; human cell; human tissue; hypothalamus; male; medulla oblongata; myelooptic neuropathy; nausea and vomiting; neuroimaging; neurologist; nonhuman; nuclear magnetic resonance imaging; pruritus; Severe acute respiratory syndrome coronavirus 2; Vero cell line; SARS-CoV-2 vaccine
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Case report
Topics:
Vaccines
Language:
English
Journal:
Neuroimmunology Reports
Year:
2023
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS