Antibiotics in Paediatrics: A Boon or a Bane?
Anti-Infective Agents
; 21(2):1-17, 2023.
Article
in English
| EMBASE | ID: covidwho-2315951
ABSTRACT
Antibiotics play an essential role in antimicrobial therapy. Among all the medications in children, the most commonly prescribed therapy is antibiotics and is currently the indispensable means to cure transmissible diseases. Several categories of antibiotics have been introduced into clinical practice to treat microbial infections. Reducing the unnecessary use of antibiotics is a global need and priority. This article aims to provide better knowledge and understanding of the impact of the early use of antibiotics. This article highlights the proper use of antibiotics in chil-dren, detailing how early and inappropriate use of antibiotics affect the gut microbiome during normal body development and consequently affect the metabolism due to diabetes mellitus, obe-sity, and recurrence of infections, such as UTI. Several new antibiotics in their development stage, newly marketed antibiotics, and some recalled and withdrawn from the market are also briefly discussed in this article. This study will help future researchers in exploring the latest information about antibiotics used in paediatrics.Copyright © 2023 Bentham Science Publishers.
Antibiotic; antibiotic resistance; ceftaroline; macrolides; microbiome; paediatrics; antimicrobial therapy; antiviral activity; asthma; child; childhood mortality; coronavirus disease 2019; diabetes mellitus; genetic resistance; human; immune system; insulin resistance; intestine flora; metabolism; obesity; pediatrics; short survey; side effect/si [Side Effect]; urinary tract infection; amikacin; amoxicillin; amoxicillin plus clavulanic acid; antibiotic agent/ae [Adverse Drug Reaction]; antibiotic agent/pv [Special Situation for Pharmacovigilance]; avibactam plus ceftazidime; azithromycin; C reactive protein/ec [Endogenous Compound]; cefalexin; cefazolin; cefiderocol; cefixime; cefotaxime; ceftazidime; ceftolozane plus tazobactam; cephalosporin; chloramphenicol; cilastatin; ciprofloxacin; clarithromycin; clindamycin; cloxacillin; cotrimoxazole; dalbavancin; doxycycline; eravacycline; fidaxomicin; gentamicin; imipenem; lefamulin; macrolide; meropenem; metronidazole; nitrofurantoin; nitroimidazole; omadacycline; oritavancin; penicillin G; penicillin V; piperacillin plus tazobactam; plazomicin; pretomanid; rifamycin; sarecycline; tedizolid; telavancin; vancomycin
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Anti-Infective Agents
Year:
2023
Document Type:
Article
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