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Role of phytocompounds as the potential anti-viral agent: an overview.
Mohanty, Swati Sucharita; Sahoo, Chita Ranjan; Paidesetty, Sudhir Kumar; Padhy, Rabindra Nath.
  • Mohanty SS; Department of Medical Oncology, IMS & Sum Hospital, Siksha 'O' Anusandhan Deemed to Be University, Bhubaneswar, 751003, Odisha, India. swatimohanty16@gmail.com.
  • Sahoo CR; Central Research Laboratory, IMS & Sum Hospital, Siksha 'O' Anusandhan Deemed to Be University, Bhubaneswar, 751003, Odisha, India.
  • Paidesetty SK; Department of Health Research, Ministry of Health & Family Welfare, Govt. of India, ICMR-Regional Medical Research Centre, 751023, Bhubaneswar, India.
  • Padhy RN; Department of Medicinal Chemistry, School of Pharmaceutical Science, Siksha 'O' Anusandhan Deemed to Be University, Bhubaneswar, 751003, Odisha, India.
Naunyn Schmiedebergs Arch Pharmacol ; 2023 May 09.
Article in English | MEDLINE | ID: covidwho-2317321
ABSTRACT
Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines' developments remain uncanny. In this century of the biological era, human viruses act predominantly as versatile spreaders. The infection of the present COVID-19 virus is up in the air; blithely, the integument of medicinal chemistry approaches, particularly bioactive derived phytocompounds could be helpful to control those human viruses, recognized in the last 100 years. Indeed, natural products are being used for various therapeutic purposes. The major bioactive phytocompounds are chemically containing coumarin, thiosulfonate, steroid, polysaccharide, tannin, lignin, proanthocyanidin, terpene, quinone, saponin, flavonoid, alkaloid, and polyphenol, that are documented for inhibitory action against several viral infections. Mostly, about 20-30% of plants from tropical or temperate regions are known to have some antiviral activity. This comprehensive analysis of bioactive-derived phytocompounds would represent a significant impact and might be helpful for antiviral research and the current state of viral treatments.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2023 Document Type: Article Affiliation country: S00210-023-02517-2

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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2023 Document Type: Article Affiliation country: S00210-023-02517-2