Safety Monitoring of Covid-19 Vaccine: In a Tertiary Care Hospital in Haryana
International Journal of Pharmacy and Pharmaceutical Sciences
; 15(3):35-37, 2023.
Article
in English
| EMBASE | ID: covidwho-2317581
ABSTRACT
Objective:
The present study aimed to ensure the safety and related potential adverse effects following ChAdOx1 nCoV-19 vaccination (AZD1222) in a scenario when numerous vaccines have been approved on an emergency basis by the WHO and other regulatory agencies to prevent the widespread of COVID-19 infection and to decrease the associated mortality and morbidity. Method(s) This study was an open, non-comparative, non-interventional, observational study conducted on healthcare workers of BPS Govt. medical college for women and elderly people who received the first dose of COVID-19 vaccinationChAdOx1 nCoV-19 vaccine (AZD1222) by conducting their interviews and recording the dataResults:
Between January and March 2021, a total of 1907 participants were enrolled in this study. Out of 1907 recipients, 70 recipients reports adverse drug events following vaccination. Myalgia (0.629%), headache (1.31%), fever >=(37.5 degreeC, 0.839%) and fever with chills (>= 37.5 degreeC, 1.048) were the most common adverse events after the first dose of vaccination of ChAdOx1 nCoV-19 vaccine (AZD1222. Throat irritation (0.209 %) and Generalised itching (0.262) were the least common adverse events. Conclusion(s) ChAdOx1 nCoV-19 (Astrazeneca) has an acceptable safety profile as observed in this study. To our knowledge, very few studies are done that review the safety of COVID-19 vaccines. Further safety data from a larger sample size and of longer duration are warranted to establish safetyCopyright © 2023 Innovare Academics Sciences Pvt. Ltd. All rights reserved.
Adverse drug reactions; ChAdOx1 nCoV-19 vaccine; Covid 19 vaccine; Vaccination; adult; adverse drug reaction; article; chill/si [Side Effect]; coronavirus disease 2019; dizziness/si [Side Effect]; drug safety; female; fever/si [Side Effect]; Haryana; headache/si [Side Effect]; health care personnel; human; injection site pain/si [Side Effect]; interview; male; mortality; myalgia/si [Side Effect]; nausea and vomiting/si [Side Effect]; observational study; pharmacist; pruritus/si [Side Effect]; questionnaire; sample size; skin redness/si [Side Effect]; tertiary care center; virus particle; vaxzevria/ae [Adverse Drug Reaction]
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Vaccines
Language:
English
Journal:
International Journal of Pharmacy and Pharmaceutical Sciences
Year:
2023
Document Type:
Article
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