Your browser doesn't support javascript.
Pharmacokinetics of cefiderocol during extracorporeal membrane oxygenation: A case report.
Riera, Jordi; Domenech, Laura; García, Sonia; Pau, Alba; Sosa, Manuel; Domenech, Josep; Palmada, Clara; Torrella, Pau; Sánchez, Ariadna; Lamora, Anna; Gallart, Elisabet; Girón, Pilar; Nuvials, Xavier; Ferrer, Ricard.
  • Riera J; Critical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Domenech L; Sepsis, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
  • García S; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Pau A; Pharmacy Department, Vall D'Hebron University Hospital, Barcelona, Spain.
  • Sosa M; Pharmacy Department, Vall D'Hebron University Hospital, Barcelona, Spain.
  • Domenech J; Pharmacy Department, Vall D'Hebron University Hospital, Barcelona, Spain.
  • Palmada C; Critical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Torrella P; Sepsis, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
  • Sánchez A; Critical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Lamora A; Sepsis, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
  • Gallart E; Critical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Girón P; Sepsis, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
  • Nuvials X; Critical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Ferrer R; Sepsis, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
Perfusion ; 38(1_suppl): 40-43, 2023 05.
Article in English | MEDLINE | ID: covidwho-2318599
ABSTRACT
Patients with extracorporeal membrane oxygenation (ECMO) support do frequently receive broad-spectrum antibiotics, due to the high frequency of infection by multidrug resistant microorganisms. The extracorporeal circuit can alter the pharmacokinetics (PK) of administered drugs, and in the case of antibiotics this may lead to treatment failure. Cefiderocol is a new cephalosporin that exhibits excellent in vitro activity against many multidrug-resistant (MDR) microorganisms, but there is no published data about the modifications of its PK in patients with ECMO support. Herein we report the results of a pharmacokinetic investigation of cefiderocol in a critically ill patient receiving extracorporeal respiratory support.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation Type of study: Case report Limits: Humans Language: English Journal: Perfusion Journal subject: Cardiology Year: 2023 Document Type: Article Affiliation country: 02676591231160462

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation Type of study: Case report Limits: Humans Language: English Journal: Perfusion Journal subject: Cardiology Year: 2023 Document Type: Article Affiliation country: 02676591231160462