Analytical and biomedical applications of microfluidics in traditional Chinese medicine research
TrAC - Trends in Analytical Chemistry
; 158 (no pagination), 2023.
Article
in English
| EMBASE | ID: covidwho-2319236
ABSTRACT
Traditional Chinese medicine (TCM) has significant benefits in the prevention and treatment of diseases due to its unique theoretical system and research techniques. However, there are still key issues to be resolved in the full interpretation and use of TCM, such as vague active compounds and mechanism of action. Therefore, it is promising to promote the research on TCM through innovative strategies and advanced cutting-edge technologies. Microfluidic chips have provided controllable unique platforms for biomedical applications in TCM research with flexible composition and large-scale integration. In this review, the analysis and biomedical applications of microfluidics in the field of TCM are highlighted, including quality control of Chinese herbal medicines (CHMs), delivery of CHMs, evaluation of pharmacological activity as well as disease diagnosis. Finally, potential challenges and prospects of existing microfluidic technologies in the inheritance and innovation of TCM are discussed.Copyright © 2022 Elsevier B.V.
Disease diagnosis; Drug delivery; Microfluidics; Quality control; Toxicity and pharmacological evaluation; Traditional Chinese medicine; biomedical engineering; cancer diagnosis; cell assay; chemical fingerprinting; Chinese medicine; coronavirus disease 2019; drug activity; drug delivery system; drug screening; human; immune system; infection; intestine; liquid liquid extraction; matrix assisted laser desorption ionization time of flight mass spectrometry; nanofabrication; prenatal diagnosis; review; spheroid cell; alkaloid; heavy metal; hydrogel; pesticide; kidney on a chip; lab on a chip; liver on a chip; lung on a chip; microneedle; tumor on a chip
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Traditional medicine
Language:
English
Journal:
TrAC - Trends in Analytical Chemistry
Year:
2023
Document Type:
Article
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