COVID-19 in children with severe aplastic anemia
Pediatric Hematology Oncology Journal
; 7(3):92-95, 2022.
Article
in English
| Scopus | ID: covidwho-2319837
ABSTRACT
Introduction:
Coronavirus disease 2019 (COVID-19) affects children but mostly has mild course. There is meagre published data on the impact of COVID-19 illness in children with Severe Aplastic anemia (SAA). We describe our experience of managing COVID-19 in children with SAA.Method:
Three children of SAA who developed SARS-CoV-2 infection are included in this study.Results:
Patient 1 was post Immunosuppressive therapy (IST) for SAA and had an asymptomatic course and uneventful recovery. Patient 2 was several months post IST with no response and had an asymptomatic COVID-19 illness but had delayed viral clearance, however he succumbed to bacterial sepsis soon after. Patient 3 was awaiting IST and while he contracted severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) infection, he had symptomatic COVID-19 illness followed by bacterial and fungal sepsis to which he succumbed.Conclusion:
COVID-19 in children with SAA can be mild to fatal course and virus may have delayed clearance. It can lead to delay in therapy of SAA. © 2022 Pediatric Hematology Oncology Chapter of Indian Academy of Pediatrics
Children; COVID-19; Immunosuppressive therapy; Severe aplastic anemia; aplastic anemia; Article; asymptomatic coronavirus disease 2019; case report; child; coronavirus disease 2019; female; human; immunosuppressive treatment; interstitial pneumonia; male; multiple organ failure; reverse transcription polymerase chain reaction; sepsis; septic shock; Severe acute respiratory syndrome coronavirus 2; teleconsultation
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Pediatric Hematology Oncology Journal
Year:
2022
Document Type:
Article
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