The association between nutrients and occurrence of COVID-19 outcomes in the population of Western Iran: A cohort study.
Clin Respir J
; 17(6): 589-602, 2023 Jun.
Article
in English
| MEDLINE | ID: covidwho-2320066
ABSTRACT
INTRODUCTION:
The study aimed to determine the association between nutrients (micronutrients, macronutrients, and antioxidants) and the occurrence of COVID-19-related outcomes (morbidity and hospitalization) using a cohort study in Western Iran.METHODS:
The basic study information was collected from February 2019 to February 2020 from the baseline phase of the Dehgolan Prospective Cohort Study (DehPCS). The primary outcomes in this study included risk of contracting COVID-19 and hospitalization due to it at a specific time. To compare these outcomes based on different nutritional groups (macronutrients or micronutrients), Kaplan-Meier chart and log rank test were used. Also, univariate and multivariate regression models were used to investigate the association between different nutritional groups and desired outcomes (risk of contracting COVID-19 and hospitalization due to it at a certain time).RESULTS:
The results showed that people having an insufficient intake of selenium (HR 1.180; % 95 CI 1.032-2.490; P 0.042), vitamin A (HR 1.119; % 95 CI 1.020-1.442; p 0.033), and vitamin E (HR 1.544; % 95 CI 1.136-3.093; p 0.039) were significantly more infected with COVID-19 than the ones who had a sufficient intake of these nutrients. Also, the results showed that people having an insufficient intake of selenium (HR 2.130; % 95 CI 1.232-3.098; p 0.018) and vitamin A (HR 1.200; % 95 CI 1.000-2.090; p 0.043) were significantly hospitalized more than the ones who had a sufficient intake of these nutrients.CONCLUSION:
Insufficient intake of selenium and vitamins A and E can significantly increase the incidence of COVID-19 and hospitalization due to it.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Selenium
/
COVID-19
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Clin Respir J
Year:
2023
Document Type:
Article
Affiliation country:
Crj.13632
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