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Endotheliopathy in Acute COVID-19 and Long COVID.
Vassiliou, Alice G; Vrettou, Charikleia S; Keskinidou, Chrysi; Dimopoulou, Ioanna; Kotanidou, Anastasia; Orfanos, Stylianos E.
  • Vassiliou AG; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
  • Vrettou CS; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
  • Keskinidou C; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
  • Dimopoulou I; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
  • Kotanidou A; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
  • Orfanos SE; First Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 106 76 Athens, Greece.
Int J Mol Sci ; 24(9)2023 May 04.
Article in English | MEDLINE | ID: covidwho-2320117
ABSTRACT
The pulmonary endothelium is a highly regulated organ that performs a wide range of functions under physiological and pathological conditions. Since endothelial dysfunction has been demonstrated to play a direct role in sepsis and acute respiratory distress syndrome, its role in COVID-19 has also been extensively investigated. Indeed, apart from the COVID-19-associated coagulopathy biomarkers, new biomarkers were recognised early during the pandemic, including markers of endothelial cell activation or injury. We systematically searched the literature up to 10 March 2023 for studies examining the association between acute and long COVID-19 severity and outcomes and endothelial biomarkers.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vascular Diseases / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2023 Document Type: Article Affiliation country: Ijms24098237

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vascular Diseases / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2023 Document Type: Article Affiliation country: Ijms24098237