Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients.
BMC Microbiol
; 23(1): 123, 2023 05 09.
Article
in English
| MEDLINE | ID: covidwho-2320384
ABSTRACT
COVID-19 has emerged as a global pandemic, challenging the world's economic and health systems. Human oral microbiota comprises the second largest microbial community after the gut microbiota and is closely related to respiratory tract infections; however, oral microbiomes of patients who have recovered from COVID-19 have not yet been thoroughly studied. Herein, we compared the oral bacterial and fungal microbiota after clearance of SARS-CoV-2 in 23 COVID-19 recovered patients to those of 29 healthy individuals. Our results showed that both bacterial and fungal diversity were nearly normalized in recovered patients. The relative abundance of some specific bacteria and fungi, primarily opportunistic pathogens, decreased in recovered patients (RPs), while the abundance of butyrate-producing organisms increased in these patients. Moreover, these differences were still present for some organisms at 12 months after recovery, indicating the need for long-term monitoring of COVID-19 patients after virus clearance.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Microbiota
/
Mycobiome
/
COVID-19
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
BMC Microbiol
Journal subject:
Microbiology
Year:
2023
Document Type:
Article
Affiliation country:
S12866-023-02872-3
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