Research progress of COVID‑19 vaccination in organ transplant recipients

ABSTRACT

The pandemic has been relieved all over the world with the popularity of the COVID-19 vaccine. However, transplant recipients are still at risk of COVID-19 because they require lifelong immunosuppressive therapy, and the effectiveness and safety of vaccination are often lower than that of the normal population. Meanwhile, the effectiveness and safety of COVID-19 vaccination have not yet been demonstrated in the immunosuppressive population, due to the lack of proper clinical trials on this group. Therefore, the present study reviews the current situation and concept of vaccination for patients after organ transplantation, and the effectiveness and safety of the new coronavirus vaccine which has been put into use in China, so as to provide a theoretical basis for the vaccination of COVID-19 vaccine for these patients, and to reduce the risk of COVID-19 infection in these patients. © 2022 Editorial Board of Medical Journal of Wuhan University. All rights reserved.