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An overview on medicinal plants used for combating coronavirus: Current potentials and challenges.
Abou Baker, Doha H; Hassan, Emad M; El Gengaihi, Souad.
  • Abou Baker DH; Medicinal and Aromatic Plants Dept., Pharmaceutical and Drug Industries Institute, National Research Centre, Cairo, Egypt.
  • Hassan EM; Medicinal and Aromatic Plants Dept., Pharmaceutical and Drug Industries Institute, National Research Centre, Cairo, Egypt.
  • El Gengaihi S; Medicinal and Aromatic Plants Dept., Pharmaceutical and Drug Industries Institute, National Research Centre, Cairo, Egypt.
J Agric Food Res ; 13: 100632, 2023 Sep.
Article in English | MEDLINE | ID: covidwho-2321347
ABSTRACT
Worldwide, Severe acute respiratory syndrome Coronavirus (SARS-CoV-2) pandemic crisis, causing many morbidities, mortality, and devastating impact on economies, so the current outbreak of the CoV-2 is a major concern for global health. The infection spread quickly and caused chaos in many countries around the world. The slow discovery of CoV-2 and the limited treatment options are among the main challenges. Therefore, the development of a drug that is safe and effective against CoV-2 is urgently needed. The present overview briefly summarizes CoV-2 drug targets ex RNA-dependent RNA polymerase (RdRp), papain-like protease (PLpro), 3-chymotrypsin-like protease (3CLpro), transmembrane serine protease enzymes (TMPRSS2), angiotensin-converting enzyme 2 (ACE2), structural protein (N, S, E, and M), and virulence factors (NSP1, ORF7a, and NSP3c) for which drug design perspective can be considered. In addition, summarize all anti-COVID-19 medicinal plants and phytocompounds and their mechanisms of action to be used as a guide for further studies.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Traditional medicine Language: English Journal: J Agric Food Res Year: 2023 Document Type: Article Affiliation country: J.jafr.2023.100632

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Full text: Available Collection: International databases Database: MEDLINE Topics: Traditional medicine Language: English Journal: J Agric Food Res Year: 2023 Document Type: Article Affiliation country: J.jafr.2023.100632