Proning in COVID-19 Acute Respiratory Distress Syndrome: Role of Paralytics.
Crit Care Explor
; 4(2): e0646, 2022 Feb.
Article
in English
| MEDLINE | ID: covidwho-2322549
ABSTRACT
Although proning is beneficial to acute respiratory distress syndrome, impressions vary about its efficacy. Some providers believe that paralysis is required to facilitate proning. We studied impact of paralysis on prone-induced gas exchange improvements and provider attitudes regarding paralytics. DESIGN:
Observational.SETTING:
University of California San Diego. PATIENTS Intubated COVID acute respiratory distress syndrome patients.INTERVENTIONS:
None. MEASUREMENTS AND MAINRESULTS:
1) Changes in Pao2Fio2 and Spo2Fio2 ratios before and after proning with and without paralytics, 2) adverse events during proning with and without paralytics, and 3) nurse and physician attitudes about efficacy/safety of proning with and without paralytics. Gas-exchange improvement with proning was similar with and without paralytics (with no serious adverse events). Survey results showed similar attitudes between nurses and physicians about proning efficacy but differing attitudes about the need for paralytics with proning.CONCLUSIONS:
Findings support use of proning and may help in design of randomized trials to assess paralytics in acute respiratory distress syndrome management.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Language:
English
Journal:
Crit Care Explor
Year:
2022
Document Type:
Article
Affiliation country:
Cce.0000000000000646
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