Patient with severe acute respiratory syndrome coronavirus 2 nosocomial infection undergoing superselective intra-arterial chemoradiation therapy for maxillary gingival carcinoma: A case report

ABSTRACT

BackgroundThe ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has changed cancer treatment. However, specific guidelines for patients with oral cancer and SARS-CoV-2 infection, especially for chemoradiation therapy (CRT), are lacking. Case PresentationWe report a case of a woman with oral squamous cell carcinoma diagnosed with SARS-CoV-2 nosocomial infection, although she had no COVID-19 symptoms, while undergoing superselective intra-arterial CRT. She received sotrovimab while continuing CRT and achieved a complete response. ConclusionThe general condition of the patient and the CRT regimen characteristics should be considered in the treatment of patients with COVID-19 and cancer.