Long-lasting brain fog is related with severity clusters of symptoms in COVID-19 patients. Background: COVID-19 patients may experience lon-lasting symptoms from weeks to even months. Aim: to evaluate long-term cognitive impairment based on the severity
Revista Medica de Chile
; 150(11):1484-1492, 2022.
Article
in English
| GIM | ID: covidwho-2324327
ABSTRACT
Background:
COVID-19 patients may experience lon-lasting symptoms from weeks to even months.Aim:
To evaluate long-term cognitive impairment based on the severity of symptoms of COVID-19 infection in a primary health system setting. Material andmethods:
From a database of 363 patients, 83 cases aged 47 +or- 15 years, (58% females) were selected from June to August 2020. In patients who survived the virus, 24 infection-related symptoms were collected to create three severity clusters (mild, moderate, and severe). The follow-up time was at least seven months. Comparing the first two clusters with the severe cluster, the existence of brain fog and risk factors (obesity, hypertension, diabetes, chronic lung disease, and hypothyroidism) were analyzed.Results:
Thirty-one patients (37%) had persistent symptoms lasting up to 240 days. Fifty-one patients (61%) experienced brain fog. Concentration was affected by symptom severity (odds ratio [OR] 3.63, 95% confidence interval [CI] 1.26-10.46, p = 0.02). Short- or long-term memory loss was not affected. Moreover, symptom severity was related to brain fog (OR 3.16, 95% CI 1.05-9.51, p = 0.04). Patients with persistent symptoms had a concentration impairment associated with severity patterns (OR 24.3, 95% CI 1.73-340.11, p = 0.03).Conclusions:
Brain fog is associated with symptom severity in COVID-19 survivors and lasts for more than eight months.
50-99-7; 9004-10-8; symptoms; human diseases; coronavirus disease 2019; viral diseases; patients; anthropometric dimensions; blood pressure; blood sugar; blood vessels; body composition; body fat; body mass index; cardiovascular diseases; diabetes mellitus; glucose; hypertension; hypothyroidism; insulin; obesity; thyroid diseases; thyroid gland; vascular diseases; chronic course; chronic diseases; memory; Severe acute respiratory syndrome coronavirus 2; man; Chile; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Andean Group; APEC countries; high income countries; Latin America; America; South America; very high Human Development Index countries; post-acute COVID-19 syndrome; SARS-CoV-2; viral infections; anthropometric measurements; blood glucose; glucose in blood; dextrose; high blood pressure; fatness; thyroid; blood vessel disorders
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Collection:
Databases of international organizations
Database:
GIM
Type of study:
Cohort study
/
Experimental Studies
/
Prognostic study
Topics:
Long Covid
Language:
English
Journal:
Revista Medica de Chile
Year:
2022
Document Type:
Article
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