Etiological structure of acute respiratory viral infections in children hospitalized in 2015-2018
Infectious Diseases: News, Opinions, Training
; 10(2):47-53, 2021.
Article
in Russian
| EMBASE | ID: covidwho-2325957
ABSTRACT
Acute respiratory viral infections (ARVI) play an important role in morbidity formation among children. At the same time, studies about the ARVI etiological structure are not enough. The article presents the results of structure analyses of ARVI in children with severe and moderate degrees of disease hospitalized in the children's clinical hospital of Novosibirsk for the period 2015-2018. This research aimed to analyze the morbidity of acute respiratory viral infections with the estimation of a causal virus in children admitted to the hospital for the period 2015-2018. Material and methods. In this study, 1137 children aged between 0 and 15 years were examined. In order to determine the etiological factor in children with damage of the upper or lower respiratory tract, by using the method of RT-PCR (AmpliSensARVI-screen-FL test systems (InterLabService, Russia), mucus from the nose and throat was examined for the presence of genetic material of viruses that cause ARVI (influenza A and B viruses, parainfluenza viruses of types 1-4, respiratory syncytial virus, metapneumovirus, four types of human coronavirus, rhinovirus, adenovirus, and bocavirus). Results. The research found that the most frequently detected pathogens are respiratory syncytial virus (23.52%), influenza A and B viruses (19.73%) and rhinovirus (19.21%). Observe the dynamics some fluctuations in the detection of mentioned viral agents and increasing of mixed infections were detected. In addition, the importance of respiratory and gastrointestinal tract combined lesions, particularly for infants and preschool - age children has been noted. Conclusion. The distribution of respiratory viruses in children with severe ARVI who required hospitalization was assessed. It was shown the significance of the respiratory syncytial infection virus, influenza virus and rhinovirus in the etiological structure of hospitalized children of different ages that damage not only the respiratory tract, but also to the gastrointestinal tract. This is an important factor in optimizing the diagnosis, treatment and prevention of viral infections in children.Copyright © Infectious Diseases News, Opinions, Training 2021.
Children; Diarrheal syndrome; Respiratory infections; acute disease/et [Etiology]; Adenoviridae; adolescent; Bocaparvovirus; child; coinfection; Coronaviridae; digestive system injury; disease severity; hospital admission; hospitalized child; human; Human respiratory syncytial virus; infant; influenza A; influenza B; lower respiratory tract infection; major clinical study; Metapneumovirus; Paramyxovirinae; pediatric hospital; preschool child; priority journal; real time reverse transcription polymerase chain reaction; review; Rhinovirus; upper respiratory tract infection; viral respiratory tract infection/et [Etiology]; polymerase chain reaction system; interlabservice AmpliSensARVI
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Etiology study
/
Prognostic study
Language:
Russian
Journal:
Infectious Diseases: News, Opinions, Training
Year:
2021
Document Type:
Article
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