Clinical and paraclinical manifestations at hospital admission (triage) and their association with severity inpatients for SARS-CoV-2 pneumonia
Medicina Interna de Mexico
; 38(1):67-74, 2022.
Article
in Spanish
| EMBASE | ID: covidwho-2326492
ABSTRACT
OBJECTIVE:
To explored whether initial laboratory data and symptoms predict further clinical outcome. MATERIALS ANDMETHODS:
Retrospective cohort study. Clinical records from March to September 2020 were revised to extract clinical-demographic characteristics, laboratory data and outcomes from patients with SARS-CoV-2 pneumonia, admitted to Centro Medico Nacional 20 de Noviembre, ISSSTE, Mexico City. RESULT(S) One thousand three patients were evaluated at the Emergency-Triage, diagnosed with SARS-CoV-2 and received further in-hospital medical attention. Most of the patients were younger than 65 years-old, male and showed co-morbid conditions, such as obesity, hypertension or diabetes mellitus. After standard therapy, 389 cases (39%) required mechanical ventilation, vasopressor agents or showed fatal outcome. Higher values of C-reactive protein, D-dimer, procalcitonin and low O2 saturation at triage significantly predicted mechanical ventilation (p <0.05) and mortality (p <0.05);while presenting symptoms like fever, myalgia, cough and ageusia showed a particular association with longer hospital stage (p < 0.05). CONCLUSION(S) Laboratory values and presenting symptoms, both evaluated at hospital admission, showed different ability to predict clinical severity, mortality and longer hospitalization time in patients with COVID-19 pneumonia. These results could be useful in possible future pandemic waves of SARS-CoV-2.Copyright © 2022 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.
covid-19; Patient outcome assessment; Pneumonia; SARS-CoV-2; Triage; adult; ageusia; article; artificial ventilation; attention; cohort analysis; coronavirus disease 2019; coughing; COVID-19 pneumonia; diabetes mellitus; fatality; fever; hospital admission; hospital patient; hospitalization; human; hypertension; major clinical study; male; mortality; myalgia; nonhuman; obesity; outcome assessment; oxygen saturation; pandemic; patient triage; retrospective study; Severe acute respiratory syndrome coronavirus 2; C reactive protein; D dimer; endogenous compound; hypertensive agent; procalcitonin
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Long Covid
Language:
Spanish
Journal:
Medicina Interna de Mexico
Year:
2022
Document Type:
Article
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