Your browser doesn't support javascript.
Vaccination status for mild and asymptomatic infections with SARS-CoV-2 Omicron BA.2 variant in Shanghai.
Yin, Yong; Lin, Jilei; Yuan, Shuhua; Tong, Shilu; He, Yi; Dong, Bin; Zhang, Fen; Chen, Erzhen; Zheng, Junhua; Wang, Wei.
  • Yin Y; Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • Lin J; Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • Yuan S; Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • Tong S; Department of Clinical Epidemiology and Biostatistics, Shanghai Children's Medical Center National Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • He Y; School of Public Health, Institute of Environment and Population Health, Anhui Medical University, Hefei, China.
  • Dong B; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Zhang F; School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.
  • Chen E; Information Technology Department, Shanghai Children's Medical Center National Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • Zheng J; Medical Department, Shanghai Children's Medical Center National Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
  • Wang W; Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
J Med Virol ; 95(5): e28767, 2023 05.
Article in English | MEDLINE | ID: covidwho-2327255
ABSTRACT
This study aimed to evaluate the effects of different vaccine regimens on mild and asymptomatic infections with SARS-CoV-2 Omicron BA.2 variant in Shanghai. All asymptomatic patients and those with mild symptoms of Omicron infections were recruited from three major Fangcang shelter hospitals between March 26, 2022 and May 20, 2022. Nucleic acid for SARS-CoV-2 by real-time reverse-transcription polymerase chain reaction methods in nasopharyngeal swabs was assessed every day during the hospitalization. The value of cycle threshold lower than 35 was considered as positive result of SARS-CoV-2. A total of 214 592 cases were included in this study. The proportion of the asymptomatic patients was 76.90% and 23.10% of the recruited patients had mild symptoms. The median (interquartile range [IQR] 25-75) duration of viral shedding (DVS) was 7 (5-10) days among all participants. The DVS varied greatly among different age groups. Children and the elderly had longer DVS compared with the adults. The booster shot of inactivated vaccine contributed to the shorter DVS in patients aged ≥70 years compared with the unvaccinated patients (8 [6-11] vs. 9 [6-12] days, p = 0.002]. Full inactivated vaccine regimen contributed to the shorter DVS in patients aged 3-6 years (7 [5-9] vs. 8 [5-10] days, p = 0.001]. In conclusion, the full inactivated vaccine regimen on children aged 3-6 years and booster inactivated vaccine regimen on the elderly aged ≥70 years appeared to be effective in reducing DVS. The booster vaccine regimen should be rigorously promoted and implemented.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Asymptomatic Infections / COVID-19 Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Long Covid / Vaccines / Variants Limits: Adult / Aged / Child / Humans Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2023 Document Type: Article Affiliation country: Jmv.28767

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Asymptomatic Infections / COVID-19 Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Long Covid / Vaccines / Variants Limits: Adult / Aged / Child / Humans Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2023 Document Type: Article Affiliation country: Jmv.28767