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The role of quercetin and curcumin in the treatment of COVID-19 infection: potential for combination of natural compounds
2nd International Conference on Biological Engineering and Medical Science, ICBioMed 2022 ; 12611, 2023.
Article in English | Scopus | ID: covidwho-2327383
ABSTRACT
SARS-CoV-2 was originally discovered in China in late 2019 and is a member of the family of enveloped, single-strand RNA viruses known as Betacorona-virus in the Coronaviridae. Since then, it has spread throughout the entire world, generating the COVID-19 epidemic, which has a high infectivity and mortality rate. Nowadays, remdesivir and a few other neutralizing antibodies have been used extensively to treat COVID-19, and other medications are now being found to have anti-coronavirus properties both in vitro and in vivo. Remdesivir's therapeutic outcomes are debatable, though, and the world still needs new antiviral medications imminently. Quercetin and curcumin, both natural compounds derived from plants, may be an option for patients with COVID-19 as a kind of treatment. Molecular docking indicates the great ability of treating COVID-19, and the combination in use may be allowed based on similar mechanisms for treating SARS-CoV-2. This review aims to summarize the role of quercetin and curcumin acting as anti-coronavirus agents, point out the lack of clinical trials of their combined use, and emphasize the use of natural compounds in treating COVID-19. © 2023 SPIE.
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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: English Journal: 2nd International Conference on Biological Engineering and Medical Science, ICBioMed 2022 Year: 2023 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: English Journal: 2nd International Conference on Biological Engineering and Medical Science, ICBioMed 2022 Year: 2023 Document Type: Article