Factors of venous thromboembolism among COVID-19 patients
Asian Journal of Pharmaceutical Research and Health Care
; 15(1):97-104, 2023.
Article
in English
| Web of Science | ID: covidwho-2328018
ABSTRACT
Context Anticoagulants are used to prevent and treat venous thromboembolism (VTE), such as deep-vein thrombosis (DVT) and pulmonary embolism (PE) in COVID-19 for better outcomes. Aim:
This study aims to explore clinical outcomes and factors affecting VTE among COVID-19 patients. Settings andDesign:
The study design involved a retrospective cohort study. StudyMethods:
Hospitalized COVID-19 patients in a tertiary hospital prescribed subcutaneous (SC) anticoagulants were included. Statistical Analysis Used Multiple logistic regression was performed to determine factors affecting VTE among subjects.Results:
A total of 450 patients were included. Types of anticoagulants include fondaparinux (n = 114, 38.1%), enoxaparin (n = 113, 37.8%), and heparin (n = 72, 24.1%). 423 (94.0%) patients were discharged well, 27 (6.0%) patients were admitted to the intensive care unit (ICU). The primary outcome was the prevalence of VTE, which occurred in 19.3% (n = 87) patients, with 80 (92.0%) reporting DVT and 7 (8.0%) reporting PE. The secondary outcome, which was the average length of hospital stay was 9.9 (+/-4.7) days. Factors of VTE occurrence were likely in patients not prescribed SC anticoagulants compared to those prescribed with SC anticoagulants (adjusted odds ratio [aOR] 54.330, 95% confidence interval [CI] 7.086, 416.526), treatment with fondaparinux compared to heparin (aOR 2.502, 95% CI 1.175, 5.327), and less likely in those discharged well compared to patients in the ICU (aOR 0.139, 95% CI 0.053, 0.361).Conclusions:
Careful monitoring is required to reduce VTE risk in COVID-19 patients.
Full text:
Available
Collection:
Databases of international organizations
Database:
Web of Science
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Language:
English
Journal:
Asian Journal of Pharmaceutical Research and Health Care
Year:
2023
Document Type:
Article
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