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Involvement of the Nervous System in SARS-CoV-2 Infection.
Li, Hao; Xue, Qun; Xu, Xingshun.
  • Li H; Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
  • Xue Q; Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China. qxue_sz@163.com.
  • Xu X; Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China. xingshunxu@suda.edu.cn.
Neurotox Res ; 38(1): 1-7, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-244976
ABSTRACT
As a severe and highly contagious infectious disease, coronavirus disease 2019 (COVID-19) has caused a global pandemic. Several case reports have demonstrated that the respiratory system is the main target in patients with COVID-19, but the disease is not limited to the respiratory system. Case analysis indicated that the nervous system can be invaded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and that 36.4% of COVID-19 patients had neurological symptoms. Importantly, the involvement of the CNS may be associated with poor prognosis and disease worsening. Here, we discussed the symptoms and evidence of nervous system involvement (directly and indirectly) caused by SARS-CoV-2 infection and possible mechanisms. CNS symptoms could be a potential indicator of poor prognosis; therefore, the prevention and treatment of CNS symptoms are also crucial for the recovery of COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Nervous System Diseases Type of study: Observational study / Prognostic study / Qualitative research Topics: Long Covid Language: English Journal: Neurotox Res Journal subject: Neurology Year: 2020 Document Type: Article Affiliation country: S12640-020-00219-8

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Nervous System Diseases Type of study: Observational study / Prognostic study / Qualitative research Topics: Long Covid Language: English Journal: Neurotox Res Journal subject: Neurology Year: 2020 Document Type: Article Affiliation country: S12640-020-00219-8