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Smell and taste alterations in Covid-19: a cross-sectional analysis of different cohorts
Non-conventional | WHO COVID | ID: covidwho-265881
ABSTRACT

BACKGROUND:

Olfactory (OD) and gustatory (GD) dysfunction have been proven to be a typical symptom of SARS-CoV-2 infection. However, their prevalence in different patient populations still needs to be clarified.

METHODS:

A cross-sectional study was performed from March 27 to April 1 2020 in Northern Italy. Physicians administered a survey-based questionnaire to SARS-CoV-2 positive patients with the aim of assessing symptoms, focusing on OD and GD. Two groups were studied patients hospitalized at ASST Spedali Civili University Hospital of Brescia (A);home-quarantined subjects (B).

RESULTS:

A total of 508 patients were enrolled 295 in Group A and 213 in Group B. Mean age (+/-SD) was 55+/-15 years;56% were men. Overall, OD and GD were present in 56% (95% CI 51-60%) and 63% (59-67%) of cases, respectively. In Group A, the prevalence of OD and GD was 44% (38-50%) and 52% (46-58%). In Group B, the prevalence of OD and GD was 72% (65-79%) and 79% (73-84%). In the entire cohort, total loss of olfaction and taste was reported in 64% and 60% of cases, respectively. OD and GD occurred as the first symptom in 10% and 11% of cases;in the remaining cases, they occurred after a mean of 4+/-3 days following the first symptom. At the time of the questionnaire, complete resolution of OD and GD was reported in 52% and 55% of cases (mean duration 9+/-5 in both).

CONCLUSIONS:

OD and GD are more prevalent in home-quarantined subjects, and they are independently associated with younger age and female gender. This article is protected by copyright. All rights reserved.
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Collection: Databases of international organizations Database: WHO COVID Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Document Type: Non-conventional

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Collection: Databases of international organizations Database: WHO COVID Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Document Type: Non-conventional