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[Analysis of CT features of 15 children with 2019 novel coronavirus infection].
Feng, K; Yun, Y X; Wang, X F; Yang, G D; Zheng, Y J; Lin, C M; Wang, L F.
  • Feng K; Department of Radiology, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
  • Yun YX; Department of Radiology, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
  • Wang XF; Department of Pediatrics, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
  • Yang GD; Department of Radiology, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
  • Zheng YJ; Department of Respiratory Medicine, Shenzhen Children's Hospital, Shenzhen 518038, China.
  • Lin CM; Department of Radiology, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
  • Wang LF; Department of Radiology, the Third People's Hospital of Shenzhen, Shenzhen 518100, China.
Zhonghua Er Ke Za Zhi ; 58(4): 275-278, 2020 Apr 02.
Article in Chinese | MEDLINE | ID: covidwho-1024679
ABSTRACT

Objective:

To explore imaging characteristics of children with 2019 novel coronavirus (2019-nCoV) infection.

Methods:

A retrospective analysis was performed on clinical data and chest CT images of 15 children diagnosed with 2019-nCoV infection. They were admitted to the Third People's Hospital of Shenzhen from January 16 to February 6, 2020. The distribution and morphology of pulmonary lesions on chest CT images were analyzed.

Results:

Among the 15 children, 5 were males and 10 females, aged from 4 to 14 years. Five of the 15 children were febrile and 10 were asymptomatic on the first visit. The first nasal or pharyngeal swab samples in all the 15 cases were positive for 2019-nCoV nucleic acid. For their first chest CT images, 6 patients had no lesions, while 9 patients had pulmonary inflammatory lesions. Seven cases had small nodular ground glass opacities and 2 cases had speckled ground glass opacities. After 3 to 5 days of treatment, 2019-nCoV nucleic acid in a second respiratory sample turned negative in 6 cases. Among them, chest CT images showed less lesions in 2 cases, no lesion in 3 cases, and no improvement in 1 case. The remaining 9 cases were still positive in a second nucleic acid test. Six patients showed similar chest CT inflammation, while 3 patients had new lesions, which were all small nodular ground glass opacities.

Conclusions:

The early chest CT images of children with 2019-nCoV infection are mostly small nodular ground glass opacities. The clinical symptoms of children with 2019-nCoV infection are nonspecific. Dynamic reexamination of chest CT and nucleic acid are important.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Tomography, X-Ray Computed / Coronavirus Infections / Betacoronavirus / Lung Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Asia Language: Chinese Journal: Zhonghua Er Ke Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112140-20200210-00071

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Tomography, X-Ray Computed / Coronavirus Infections / Betacoronavirus / Lung Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Asia Language: Chinese Journal: Zhonghua Er Ke Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112140-20200210-00071