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Use of anakinra in severe COVID-19: A case report.
Filocamo, Giovanni; Mangioni, Davide; Tagliabue, Paola; Aliberti, Stefano; Costantino, Giorgio; Minoia, Francesca; Bandera, Alessandra.
  • Filocamo G; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy. Electronic address: giovanni.filocamo@policlinico.mi.it.
  • Mangioni D; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy; University of Milan, Italy. Electronic address: davide.mangioni@unimi.it.
  • Tagliabue P; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy. Electronic address: paola.tagliabue@policlinico.mi.it.
  • Aliberti S; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy; University of Milan, Italy. Electronic address: stefano.aliberti@unimi.it.
  • Costantino G; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy; University of Milan, Italy. Electronic address: giorgio.costantino@unimi.it.
  • Minoia F; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy. Electronic address: francesca.minoia@policlinico.mi.it.
  • Bandera A; Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy; University of Milan, Italy. Electronic address: alessandra.bandera@unimi.it.
Int J Infect Dis ; 96: 607-609, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-355266
ABSTRACT
Coronavirus disease 19 is a global healthcare emergency with a high lethality rate. Relevant inflammatory cytokine storm is associated with severity of disease, and IL1 inhibition is a cornerstone treatment for hyperinflammatory diseases. We present here the case of a patient with critical COVID-19 successfully treated with IL-1 receptor antagonist (anakinra).
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Interleukin 1 Receptor Antagonist Protein Type of study: Case report / Prognostic study Limits: Humans / Male / Middle aged Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Interleukin 1 Receptor Antagonist Protein Type of study: Case report / Prognostic study Limits: Humans / Male / Middle aged Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2020 Document Type: Article