APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort.

Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David

Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David.

Kuo CL; Connecticut Convergence Institute for Translation in Regenerative Engineering, University of Connecticut Health, Farmington.
Pilling LC; Center on Aging, University of Connecticut Health, Farmington.
Atkins JL; Center on Aging, University of Connecticut Health, Farmington.
Masoli JAH; Epidemiology and Public Health Group, University of Exeter Medical School, UK.
Delgado J; Epidemiology and Public Health Group, University of Exeter Medical School, UK.
Kuchel GA; Epidemiology and Public Health Group, University of Exeter Medical School, UK.
Melzer D; Department of Healthcare for Older People, Royal Devon and Exeter Hospital, UK.

J Gerontol A Biol Sci Med Sci ; 75(11): 2231-2232, 2020 10 15.

Article in English | MEDLINE | ID: covidwho-361293

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Subject(s)

Apolipoprotein E4/genetics; Coronavirus Infections; Pandemics; Pneumonia, Viral; Aged; Betacoronavirus/physiology; Biological Specimen Banks; COVID-19; Coronavirus Infections/epidemiology; Coronavirus Infections/genetics; Coronavirus Infections/physiopathology; Coronavirus Infections/virology; England/epidemiology; Female; Genetic Predisposition to Disease; Homozygote; Humans; Male; Pneumonia, Viral/epidemiology; Pneumonia, Viral/genetics; Pneumonia, Viral/physiopathology; Pneumonia, Viral/virology; Polymorphism, Single Nucleotide; SARS-CoV-2; Severity of Illness Index; Survival Analysis

Keywords

APOE; COVID-19; Genetic

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Apolipoprotein E4 / Pandemics Type of study: Cohort study / Observational study / Prognostic study Limits: Aged / Female / Humans / Male Country/Region as subject: Europa Language: English Journal: J Gerontol A Biol Sci Med Sci Journal subject: Geriatrics Year: 2020 Document Type: Article

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