The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome?
Med Hypotheses
; 144: 109880, 2020 Nov.
Article
in English
| MEDLINE | ID: covidwho-361316
ABSTRACT
Fever has been reported as a common symptom occurring in COVID-19 illness. Over the counter antipyretics such as ibuprofen and acetaminophen are often taken by individuals to reduce the discomfort of fever. Recently, the safety of ibuprofen in COVID-19 patients has been questioned due to anecdotal reports of worsening symptoms in previously healthy young adults. Studies show that ibuprofen demonstrates superior efficacy in fever reduction compared to acetaminophen. As fever may have benefit in shortening the duration of viral illness, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response when taken during the early stages of COVID-19 illness.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Ibuprofen
/
Antipyretics
/
Fever
/
COVID-19 Drug Treatment
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Med Hypotheses
Year:
2020
Document Type:
Article
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