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Weathering the Storm: Managing Older Adults With Breast Cancer Amid COVID-19 and Beyond.
Freedman, Rachel A; Sedrak, Mina S; Bellon, Jennifer R; Block, Caroline C; Lin, Nancy U; King, Tari A; Minami, Christina; VanderWalde, Noam; Jolly, Trevor A; Muss, Hyman B; Winer, Eric P.
  • Freedman RA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sedrak MS; Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA, USA.
  • Bellon JR; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
  • Block CC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lin NU; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • King TA; Department of Surgery, Division of Breast Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • Minami C; Department of Surgery, Division of Breast Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • VanderWalde N; Department of Radiation Oncology, West Cancer Center and Research Institute, University of Tennessee Health Science Center, Memphis, TN, USA.
  • Jolly TA; Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA.
  • Muss HB; Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA.
  • Winer EP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
J Natl Cancer Inst ; 113(4): 355-359, 2021 04 06.
Article in English | MEDLINE | ID: covidwho-361366
ABSTRACT
Caring for older patients with breast cancer presents unique clinical considerations because of preexisting and competing comorbidity, the potential for treatment-related toxicity, and the consequent impact on functional status. In the context of the COVID-19 pandemic, treatment decision making for older patients is especially challenging and encourages us to refocus our treatment priorities. While we work to avoid treatment delays and maintain therapeutic benefit, we also need to minimize the risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures, myelosuppression, general chemotherapy toxicity, and functional decline. Herein, we propose multidisciplinary care considerations for the aging patient with breast cancer, with the goal to promote a team-based, multidisciplinary treatment approach during the COVID-19 pandemic and beyond. These considerations remain relevant as we navigate the "new normal" for the approximately 30% of breast cancer patients aged 70 years and older who are diagnosed in the United States annually and for the thousands of older patients living with recurrent and/or metastatic disease.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Breast Neoplasms / Interdisciplinary Communication / COVID-19 / Medical Oncology Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans Country/Region as subject: North America Language: English Journal: J Natl Cancer Inst Year: 2021 Document Type: Article Affiliation country: Jnci

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Breast Neoplasms / Interdisciplinary Communication / COVID-19 / Medical Oncology Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans Country/Region as subject: North America Language: English Journal: J Natl Cancer Inst Year: 2021 Document Type: Article Affiliation country: Jnci