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Use of corticosteroids in asthma and COPD patients with or without COVID-19.
Hasan, Syed Shahzad; Capstick, Toby; Zaidi, Syed Tabish Razi; Kow, Chia Siang; Merchant, Hamid A.
  • Hasan SS; Department of Pharmacy, University of Huddersfield, Huddersfield, UK. Electronic address: s.hasan@hud.ac.uk.
  • Capstick T; Leeds Teaching Hospitals NHS Trust, St. James's University Hospital, Leeds, UK.
  • Zaidi STR; School of Healthcare, University of Leeds, Leeds, UK.
  • Kow CS; School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia.
  • Merchant HA; Department of Pharmacy, University of Huddersfield, Huddersfield, UK.
Respir Med ; 170: 106045, 2020.
Article in English | MEDLINE | ID: covidwho-378076
ABSTRACT
The potential detrimental effects of steroids on the immune system to fight viral infections had always been a concern for patients on long term steroids in chronic conditions. A recent warning from WHO on systemic corticosteroid use amid COVID-19 raised suspicion among public and healthcare professionals regarding the safety of steroid use during the SARS-CoV-2 pandemic. The corticosteroids (inhaled and oral) are commonly prescribed in the management of asthma and COPD patients and any unsolicited changes in medications use may lead to potentially severe exacerbations and may risk patient lives. This article provides a critical review of clinical evidence and offers a detailed discussion on the safety and efficacy of corticosteroids in asthma and COPD patients, both with and without COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Asthma / Coronavirus Infections / Pulmonary Disease, Chronic Obstructive / Pandemics / Glucocorticoids Type of study: Observational study / Prognostic study / Reviews Limits: Humans Language: English Journal: Respir Med Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Asthma / Coronavirus Infections / Pulmonary Disease, Chronic Obstructive / Pandemics / Glucocorticoids Type of study: Observational study / Prognostic study / Reviews Limits: Humans Language: English Journal: Respir Med Year: 2020 Document Type: Article