ICU and Ventilator Mortality Among Critically Ill Adults With Coronavirus Disease 2019.
Crit Care Med
; 48(9): e799-e804, 2020 09.
Article
in English
| MEDLINE | ID: covidwho-378160
ABSTRACT
OBJECTIVES:
To determine mortality rates among adults with critical illness from coronavirus disease 2019.DESIGN:
Observational cohort study of patients admitted from March 6, 2020, to April 17, 2020.SETTING:
Six coronavirus disease 2019 designated ICUs at three hospitals within an academic health center network in Atlanta, Georgia, United States. PATIENTS Adults greater than or equal to 18 years old with confirmed severe acute respiratory syndrome-CoV-2 disease who were admitted to an ICU during the study period.INTERVENTIONS:
None. MEASUREMENTS AND MAINRESULTS:
Among 217 critically ill patients, mortality for those who required mechanical ventilation was 35.7% (59/165), with 4.8% of patients (8/165) still on the ventilator at the time of this report. Overall mortality to date in this critically ill cohort is 30.9% (67/217) and 60.4% (131/217) patients have survived to hospital discharge. Mortality was significantly associated with older age, lower body mass index, chronic renal disease, higher Sequential Organ Failure Assessment score, lower PaO2/FIO2 ratio, higher D-dimer, higher C-reactive protein, and receipt of mechanical ventilation, vasopressors, renal replacement therapy, or vasodilator therapy.CONCLUSIONS:
Despite multiple reports of mortality rates exceeding 50% among critically ill adults with coronavirus disease 2019, particularly among those requiring mechanical ventilation, our early experience indicates that many patients survive their critical illness.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Respiration, Artificial
/
Respiratory Distress Syndrome
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
North America
Language:
English
Journal:
Crit Care Med
Year:
2020
Document Type:
Article
Affiliation country:
CCM.0000000000004457
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