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Analysis on application of Chinese materia medica in treatment of COVID-19 by suppressing cytokine storm / 中药在抗新型冠状病毒肺炎(COVID-19)引起的细胞因子风暴中的应用分析
He, Li-Li; Gong, Pu-Yang; Feng, Yue; Zou, Wei; Wang, En-Long; Gu, Jian.
  • He, Li-Li; College of Pharmacy. Chengdu. China
  • Gong, Pu-Yang; College of Pharmacy. Chengdu. China
  • Feng, Yue; College of Pharmacy. Chengdu. China
  • Zou, Wei; College of Pharmacy. Chengdu. China
  • Wang, En-Long; College of Pharmacy. Chengdu. China
  • Gu, Jian; College of Pharmacy. Chengdu. China
Chin. Trad. Herbal Drugs ; 6(51): 1375-1385, 20200328.
Article in Chinese | WHO COVID, ELSEVIER | ID: covidwho-380619
ABSTRACT
At the end of December, 2019, a novel coronavirus disease (COVID-19) outbreak was found in China. COVID-19 spreads all over 268 countries, and more than 70 000 people got infected till February 23th, 2020. COVID-19 can result in acute respiratory distress syndrome and multiple organ failure due to its strong infectivity and extensive spread. These severe complications are believed to be the consequence of cytokine storm caused by the virus infection. In the “Diagnosis and treatment of novel coronavirus pneumonia”, glucocorticoid is recommended as the immunosuppressive agents to prevent acute immune reaction in critical patients. However, the usage of glucocorticoid may bring severe residual effects such as superinfection risks, prolonged course of disease. Traditional Chinese medicine might have advantages in the moderation of immune system. Actually, TCM is now applied in the treatment of COVID-19 clinically, and exhibits excellent therapeutic effects. In this review, the potential usage of TCM or traditional prescriptions in inhibiting cytokine storm and treating in acute lung injury were analyzed, which would be an effective strategy for the treatment of COVID-19.

Full text: Available Collection: International databases Database: WHO COVID / ELSEVIER Topics: Traditional medicine Language: Chinese Journal: Chin. Trad. Herbal Drugs Year: 2020 Document Type: Article Institution/Affiliation country: College of Pharmacy/China

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Full text: Available Collection: International databases Database: WHO COVID / ELSEVIER Topics: Traditional medicine Language: Chinese Journal: Chin. Trad. Herbal Drugs Year: 2020 Document Type: Article Institution/Affiliation country: College of Pharmacy/China