Evaluation of World Health Organization-Recommended Hand Hygiene Formulations.
Emerg Infect Dis
; 26(9): 2064-2068, 2020 Sep.
Article
in English
| MEDLINE | ID: covidwho-381792
ABSTRACT
As a result of the coronavirus disease pandemic, commercial hand hygiene products have become scarce and World Health Organization (WHO) alcohol-based hand rub formulations containing ethanol or isopropanol are being produced for hospitals worldwide. Neither WHO formulation meets European Norm 12791, the basis for approval as a surgical hand preparation, nor satisfies European Norm 1500, the basis for approval as a hygienic hand rub. We evaluated the efficacy of modified formulations with alcohol concentrations in mass instead of volume percentage and glycerol concentrations of 0.5% instead of 1.45%. Both modified formulations met standard requirements for a 3-minute surgical hand preparation, the usual duration of surgical hand treatment in most hospitals in Europe. Contrary to the originally proposed WHO hand rub formulations, both modified formulations are appropriate for surgical hand preparation after 3 minutes when alcohol concentrations of 80% wt/wt ethanol or 75% wt/wt isopropanol along with reduced glycerol concentration (0.5%) are used.
Keywords
2019 novel coronavirus disease; COVID-19; SARS-CoV-2; WHO formulation; World Health Organization; alcohol-based hand rub; coronavirus disease; glycerol; hand hygiene; hand sanitizer; modified; respiratory infections; severe acute respiratory syndrome coronavirus 2; surgical hand preparation; viruses; zoonoses
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Pandemics
/
Hand Hygiene
/
Hand Sanitizers
/
Betacoronavirus
Type of study:
Experimental Studies
Limits:
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Emerg Infect Dis
Journal subject:
Communicable Diseases
Year:
2020
Document Type:
Article
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