Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19) using convalescent plasma.
Transfus Apher Sci
; 59(5): 102820, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-398907
ABSTRACT
BACKGROUND:
Because treatment options for coronavirus disease 2019 (COVID-19) are very limited, the use of convalescent plasma has bee explored. CASE PRESENTATION AND TREATMENT A male centenarian with cough and dyspnea for 2 months was diagnosed with COVID-19. Without effective treatments and with the increased risks of antiviral therapy for the elderly, this patient was given convalescent plasma. The viral load, complete blood count, inflammatory indicators, vital signs, and clinical symptoms were observed before and after COVID-19 convalescent plasma transfusion.RESULTS:
After convalescent plasma transfusion, significant improvement was observed on laboratory indicators and clinical symptoms of the patient. Concurrently, SARS-CoV-2 viral load decreased sharply after the first transfusion (from 2.55 × 104 to 1.39 × 103 copies/mL) and became undetectable after the second transfusion.CONCLUSIONS:
With the substantial increase of COVID-19 in recent months,treatment for elderly patients has become restricted in some countries. The successful treatment of this 100-year-old patient using convalescent plasma suggests that we should consider adding convalescent plasma in th management of the elderly.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Case report
/
Experimental Studies
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Transfus Apher Sci
Journal subject:
Hematology
Year:
2020
Document Type:
Article
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