SARS-CoV-2 Phylogenetic Analysis, Lazio Region, Italy, February-March 2020.

Bartolini, Barbara; Rueca, Martina; Gruber, Cesare Ernesto Maria; Messina, Francesco; Carletti, Fabrizio; Giombini, Emanuela; Lalle, Eleonora; Bordi, Licia; Matusali, Giulia; Colavita, Francesca; Castilletti, Concetta; Vairo, Francesco; Ippolito, Giuseppe; Capobianchi, Maria Rosaria; Di Caro, Antonino

Bartolini, Barbara; Rueca, Martina; Gruber, Cesare Ernesto Maria; Messina, Francesco; Carletti, Fabrizio; Giombini, Emanuela; Lalle, Eleonora; Bordi, Licia; Matusali, Giulia; Colavita, Francesca; Castilletti, Concetta; Vairo, Francesco; Ippolito, Giuseppe; Capobianchi, Maria Rosaria; Di Caro, Antonino.

Emerg Infect Dis ; 26(8): 1842-1845, 2020 08.

Article in English | MEDLINE | ID: covidwho-403054

ABSTRACT

ABSTRACT

We report phylogenetic and mutational analysis of severe acute respiratory syndrome coronavirus 2 virus strains from the Lazio region of Italy and provide information about the dynamics of virus spread. Data suggest effective containment of clade V strains, but subsequently, multiple waves of clade G strains were circulating widely in Europe.

Subject(s)

Betacoronavirus/genetics; Coronavirus Infections/epidemiology; Coronavirus Infections/transmission; Pandemics; Phylogeny; Pneumonia, Viral/epidemiology; Pneumonia, Viral/transmission; RNA, Viral/genetics; Adult; Aged; Betacoronavirus/classification; Betacoronavirus/pathogenicity; Bronchoalveolar Lavage Fluid/virology; COVID-19; COVID-19 Testing; Clinical Laboratory Techniques/methods; Coronavirus Infections/diagnosis; Coronavirus Infections/virology; Female; High-Throughput Nucleotide Sequencing; Hospitalization; Humans; Italy/epidemiology; Male; Middle Aged; Mutation; Nasopharynx/virology; Pneumonia, Viral/diagnosis; Pneumonia, Viral/virology; Prospective Studies; Real-Time Polymerase Chain Reaction; SARS-CoV-2; Severity of Illness Index; Time Factors

Keywords

COVID-19; Italy; SARS-CoV-2; coronavirus disease; full genome sequence; phylogenetic tree; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Phylogeny / Pneumonia, Viral / RNA, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2020 Document Type: Article

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