ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia.

Rivellese, Felice; Prediletto, Edoardo

Rivellese, Felice; Prediletto, Edoardo.

Rivellese F; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom. Electronic address: f.rivellese@qmul.ac.uk.
Prediletto E; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Autoimmun Rev ; 19(6): 102536, 2020 Jun.

Article in English | MEDLINE | ID: covidwho-41548

Subject(s)

Betacoronavirus/pathogenicity; Coronavirus Infections/pathology; Coronavirus Infections/virology; Down-Regulation; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral/pathology; Respiratory Distress Syndrome/pathology; Air Pollution/statistics & numerical data; Alveolar Epithelial Cells/metabolism; Alveolar Epithelial Cells/pathology; Alveolar Epithelial Cells/virology; Angiotensin-Converting Enzyme 2; Betacoronavirus/metabolism; COVID-19; Coronavirus Infections/epidemiology; Coronavirus Infections/immunology; Down-Regulation/drug effects; Humans; Lung Injury/pathology; Lung Injury/virology; Lymphohistiocytosis, Hemophagocytic/pathology; Lymphohistiocytosis, Hemophagocytic/virology; Macrophages/immunology; Models, Biological; Pandemics; Peptidyl-Dipeptidase A/deficiency; Pneumonia, Viral/epidemiology; Pneumonia, Viral/immunology; Pneumonia, Viral/virology; Receptors, Virus/deficiency; Receptors, Virus/metabolism; Respiratory Distress Syndrome/epidemiology; Respiratory Distress Syndrome/immunology; Respiratory Distress Syndrome/virology; SARS-CoV-2; Stem Cells/pathology; Stem Cells/virology; Viral Load; Virus Replication

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Down-Regulation / Coronavirus Infections / Peptidyl-Dipeptidase A / Betacoronavirus Type of study: Observational study Language: English Journal: Autoimmun Rev Journal subject: Allergy and Immunology Year: 2020 Document Type: Article

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