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Low prevalence and disease severity of COVID-19 in post-liver transplant recipients-A single centre experience.
Verma, Anita; Khorsandi, Shirin Elizabeth; Dolcet, Annalisa; Prachalias, Andreas; Suddle, Abid; Heaton, Nigel; Jassem, Wayel.
  • Verma A; Institute of Liver Studies, King's College Hospital, London, UK.
  • Khorsandi SE; Institute of Liver Studies, King's College Hospital, London, UK.
  • Dolcet A; Institute of Liver Studies, King's College Hospital, London, UK.
  • Prachalias A; Institute of Liver Studies, King's College Hospital, London, UK.
  • Suddle A; Institute of Liver Studies, King's College Hospital, London, UK.
  • Heaton N; Institute of Liver Studies, King's College Hospital, London, UK.
  • Jassem W; Institute of Liver Studies, King's College Hospital, London, UK.
Liver Int ; 40(8): 1972-1976, 2020 08.
Article in English | MEDLINE | ID: covidwho-436673
ABSTRACT
Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is driving a present day global pandemic. Immunosuppressed patients are regarded as a high-risk cohort. The following is a short report on COVID-19 in liver transplant recipients (n = 5) from a high volume UK liver transplant unit with a large follow-up cohort (n = 4500). Based on this limited data, liver transplant recipients appear to have a low incidence of COVID-19, with less severe symptoms than expected, when compared with the general population and other solid organ recipients. This possibly could be related to self-isolation adherence and/or the 'ideal' level of immunosuppression that favourably modulates the immune response to COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Liver Transplantation / Coronavirus Infections / Betacoronavirus Type of study: Cohort study / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Liver Int Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: Liv.14552

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Liver Transplantation / Coronavirus Infections / Betacoronavirus Type of study: Cohort study / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Liver Int Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: Liv.14552