Corticosteroid therapy for severe COVID-19 pneumonia: optimal dose and duration of administration.
Glob Health Med
; 2(3): 193-196, 2020 Jun 30.
Article
in English
| MEDLINE | ID: covidwho-437175
ABSTRACT
Severe COVID-19 is associated with a hyperinflammatory state, and corticosteroid therapy may be effective. We review the recent literature and discuss the appropriate dose and duration of corticosteroid therapy. Low-dose corticosteroid therapy is often used to treat COVID-19. However, several doses of methylprednisolone (or prednisolone) have been attempted, ranging from about 40 mg/day to 2 mg/kg/day. Doses may need to be adjusted depending on severity. Corticosteroid therapy is generally administered for a short period over several days. However, COVID-19-induced respiratory failure is often prolonged, so longer administration may be considered. Careful monitoring for complications due to corticosteroid therapy is vital.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Prognostic study
Language:
English
Journal:
Glob Health Med
Year:
2020
Document Type:
Article
Affiliation country:
Ghm.2020.01046
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