Autopsy findings from the first known death from Severe Acute Respiratory Syndrome SARS-CoV-2 in Spain.
Rev Esp Patol
; 53(3): 188-192, 2020.
Article
in English
| MEDLINE | ID: covidwho-437965
ABSTRACT
The new coronavirus SARS-CoV-2, first identified in Wuhan, China in December, 2019, can cause Severe Acute Respiratory Syndrome (SARS) with massive alveolar damage and progressive respiratory failure. We present the relevant autopsy findings of the first patient known to have died from COVID19 pneumonia in Spain, carried out on the 14th of February, 2020, in our hospital (Hospital Arnau de Vilanova-Lliria, Valencia). Histological examination revealed typical changes of diffuse alveolar damage (DAD) in both the exudative and proliferative phase of acute lung injury. Intra-alveolar multinucleated giant cells, smudge cells and vascular thrombosis were present. The diagnosis was confirmed by reverse real-time PCR assay on a throat swab sample taken during the patient's admission. The positive result was reported fifteen days subsequent to autopsy.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Respiratory Distress Syndrome
/
Autopsy
/
Coronavirus Infections
/
Pandemics
/
Betacoronavirus
/
Lung
Type of study:
Case report
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Country/Region as subject:
Asia
/
Europa
Language:
English
Journal:
Rev Esp Patol
Year:
2020
Document Type:
Article
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