In Vitro and Animal Models for SARS-CoV-2 research.

Takayama, Kazuo

Takayama, Kazuo.

Takayama K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan. Electronic address: kazuo.takayama@cira.kyoto-u.ac.jp.

Trends Pharmacol Sci ; 41(8): 513-517, 2020 08.

Article in English | MEDLINE | ID: covidwho-457060

ABSTRACT

ABSTRACT

Basic research on SARS-CoV-2 is essential to understand its detailed pathophysiology and identify best drug targets. Models that can faithfully reproduce the viral life cycle and reproduce the pathology of COVID-19 are required. Here, we briefly review the cell lines, organoids, and animal models that are currently being used in COVID-19 research.

Subject(s)

Betacoronavirus/isolation & purification; Biomedical Research/methods; Coronavirus Infections/physiopathology; Pneumonia, Viral/physiopathology; Animals; COVID-19; Cell Line; Coronavirus Infections/virology; Disease Models, Animal; Humans; In Vitro Techniques; Organoids/virology; Pandemics; Pneumonia, Viral/virology; SARS-CoV-2

Keywords

COVID-19; SARS-CoV-2; animal models; cell models; organoids

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Biomedical Research / Betacoronavirus Limits: Animals / Humans Language: English Journal: Trends Pharmacol Sci Year: 2020 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google