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The evidence of SARS-CoV-2 infection on ocular surface.
Zhang, Xian; Chen, Xuhui; Chen, Liwen; Deng, Chaohua; Zou, Xiaojing; Liu, Weiyong; Yu, Huimin; Chen, Bo; Sun, Xufang.
  • Zhang X; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Chen X; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Chen L; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Deng C; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zou X; Department of Emergency, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Liu W; Department of Clinical Laboratory, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Yu H; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Chen B; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: eyechen@aliyun.com.
  • Sun X; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: sunxufang2016@163.com.
Ocul Surf ; 18(3): 360-362, 2020 07.
Article in English | MEDLINE | ID: covidwho-45794
ABSTRACT
This is a cross-sectional study of patients who received a COVID-19 diagnosis between December 30, 2019 and February 7, 2020 at Tongji Hospital. A total of 102 patients (48 Male [47%] and 54 Female [53%]) with clinical symptoms, Rt, and chest Computed Tomography (CT) abnormalities were identified with a clinical diagnosis of COVID-19. Patients had a mean [SD] gestational age of 57.63 [14.90] years. Of a total of 102 patients identified, 72 patients (36 men [50%] and 36 women [50%]; mean [SD] age, 58.68 [14.81] years) were confirmed to have COVID-19 by laboratory diagnosis with a SARS-CoV-2 RT-PCR assay. Only two patients (2.78%) with conjunctivitis were identified from 72 patients with a laboratory confirmed COVID-19. Of those two patients, SARS-CoV-2 RNA fragments were found in ocular discharges by SARS-CoV-2 RT-PCR in only one patient. Our findings suspect the incidence of SARS-CoV-2 infection through the ocular surface is extremely low, while the nosocomial infection of SARS-CoV-2 through the eyes after occupational exposure is a potential route. To lower the SARS-CoV-2 nosocomial infection, all health care professionals should wear protective goggles. The inefficient diagnostic method and the sampling time lag may contribute to the lower positive rate of conjunctival swab samples of SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronavirus Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Ocul Surf Year: 2020 Document Type: Article Affiliation country: J.jtos.2020.03.010

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronavirus Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Ocul Surf Year: 2020 Document Type: Article Affiliation country: J.jtos.2020.03.010