COVID-19 in Parkinson's Disease Patients Living in Lombardy, Italy.
Mov Disord
; 35(7): 1089-1093, 2020 07.
Article
in English
| MEDLINE | ID: covidwho-459275
ABSTRACT
BACKGROUND:
It is unknown whether patients with PD are at greater risk of COVID-19, what their risk factors are, and whether their clinical manifestations differ from the general population.OBJECTIVES:
The study aimed to address all these issues.METHODS:
In a case-controlled survey, we interviewed 1,486 PD patients attending a single tertiary center in Lombardy, Italy and 1,207 family members (controls).RESULTS:
One hundred five (7.1%) and 92 controls (7.6%) were identified as COVID-19 cases. COVID-19 patients were younger, more likely to suffer from chronic obstructive pulmonary disease, to be obese, and vitamin D nonsupplemented than unaffected patients. Six patients (5.7%) and 7 family members (7.6%) died from COVID-19. Patients were less likely to report shortness of breath and require hospitalization.CONCLUSIONS:
In an unselected large cohort of nonadvanced PD patients, COVID-19 risk and mortality did not differ from the general population, but symptoms appeared to be milder. The possible protective role of vitamin D supplementation warrants future studies. © 2020 International Parkinson and Movement Disorder Society.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Parkinson Disease
/
Pneumonia, Viral
/
Vitamin D
/
Vitamins
/
Coronavirus Infections
/
Pulmonary Disease, Chronic Obstructive
/
Obesity
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Journal:
Mov Disord
Journal subject:
Neurology
Year:
2020
Document Type:
Article
Affiliation country:
Mds.28176
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