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COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?
Chakrabarti, Sankha Shubhra; Kaur, Upinder; Banerjee, Anindita; Ganguly, Upasana; Banerjee, Tuhina; Saha, Sarama; Parashar, Gaurav; Prasad, Suvarna; Chakrabarti, Suddhachitta; Mittal, Amit; Agrawal, Bimal Kumar; Rawal, Ravindra Kumar; Zhao, Robert Chunhua; Gambhir, Indrajeet Singh; Khanna, Rahul; Shetty, Ashok K; Jin, Kunlin; Chakrabarti, Sasanka.
  • Chakrabarti SS; 1Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India.
  • Kaur U; 2Department of Pharmacology, All India Institute of Medical Sciences, Gorakhpur, UP, India.
  • Banerjee A; 3Department of Biochemistry, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
  • Ganguly U; 3Department of Biochemistry, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
  • Banerjee T; 4Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, UP, India.
  • Saha S; 5Department of Biochemistry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
  • Parashar G; 6Department of Biotechnology, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
  • Prasad S; 7Department of Biochemistry, MM Institute of Medical Sciences & Research, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
  • Chakrabarti S; 8Health Department, Kolkata Municipal Corporation, West Bengal, India.
  • Mittal A; 9Department of Radiodiagnosis, MM Institute of Medical Sciences & Research, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
  • Agrawal BK; 10Department of General Medicine, MM Institute of Medical Sciences & Research, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
  • Rawal RK; 11Department of Chemistry, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
  • Zhao RC; 12School of Life Sciences, Shanghai University, Shanghai, China.
  • Gambhir IS; 13Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India.
  • Khanna R; 14Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India.
  • Shetty AK; 15Institute for Regenerative Medicine, Department of Molecular and Cellular Medicine, Texas A&M University College of Medicine, College Station, Texas, USA.
  • Jin K; 16Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas, USA.
  • Chakrabarti S; 17Department of Biochemistry and Central Research Cell, MM Institute of Medical Sciences & Research, Maharishi Markandeshwar (deemed to be) University, Mullana, Haryana, India.
Aging Dis ; 11(3): 480-488, 2020 May.
Article in English | MEDLINE | ID: covidwho-459276
ABSTRACT
The ongoing Corona virus (COVID-19) pandemic has witnessed global political responses of unimaginable proportions. Many nations have implemented lockdowns that involve mandating citizens not to leave their residences for non-essential work. The Indian government has taken appropriate and commendable steps to curtail the community spread of COVID-19. While this may be extremely beneficial, this perspective discusses the other reasons why COVID-19 may have a lesser impact on India. We analyze the current pattern of SARS-CoV-2 transmission, testing, and mortality in India with an emphasis on the importance of mortality as a marker of the clinical relevance of COVID-19 disease. We also analyze the environmental and biological factors which may lessen the impact of COVID-19 in India. The importance of cross-immunity, innate immune responses, ACE polymorphism, and viral genetic mutations are discussed.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Aging Dis Year: 2020 Document Type: Article Affiliation country: Ad.2020.0402

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Aging Dis Year: 2020 Document Type: Article Affiliation country: Ad.2020.0402