Successful treatment with plasma exchange followed by intravenous immunoglobulin in a critically ill patient with COVID-19.
Int J Antimicrob Agents
; 56(2): 105974, 2020 Aug.
Article
in English
| MEDLINE | ID: covidwho-637982
ABSTRACT
Here we report a case of a laboratory-confirmed 2019 novel coronavirus (2019-nCoV)-infected patient with COVID-19 (coronavirus disease 2019) who developed respiratory failure and shock accompanied by persistent diarrhoea despite conventional therapeutic interventions. The patient avoided mechanical ventilation and showed an immediate clinical and radiological improvement following treatment with intensive plasma exchange (PE) followed by intravenous immunoglobulin (IVIG). Successful therapeutic strategies in this case suggest that timely initiation of PE treatment followed by IVIG in critically ill patients with COVID-19 may prevent the disease from worsening and help to reduce the requirement for mechanical ventilation and intensive supportive care. Moreover, it may improve poor clinical outcomes of these patients.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Plasma Exchange
/
Pneumonia, Viral
/
Immunoglobulins, Intravenous
/
Critical Illness
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Int J Antimicrob Agents
Year:
2020
Document Type:
Article
Affiliation country:
J.ijantimicag.2020.105974
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