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Novel coronavirus (SARS-CoV-2) infection in a renal transplant recipient: Case report.
Ning, Ling; Liu, Lei; Li, Wenyuan; Liu, Hongtao; Wang, Jizhou; Yao, Ziqin; Zhang, Shengyu; Zhao, Desheng; Nashan, Björn; Shen, Aizong; Liu, Lianxin; Li, Lei.
  • Ning L; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Liu L; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Li W; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Liu H; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Wang J; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Yao Z; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Zhang S; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Zhao D; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Nashan B; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Shen A; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Liu L; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
  • Li L; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, P.R. China.
Am J Transplant ; 20(7): 1864-1868, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-46462
ABSTRACT
An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure, and no pharmacological therapies of proven efficacy yet exist. We report a case of SARS-CoV-2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of cyclosporine in patients treated with lopinavir/ritonavir; the routine treatment of corticosteroid can be continued. This is a rare report of SARS-CoV-2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity, and outcome of SARS-CoV-2 infections in solid organ transplant recipients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunosuppression Therapy / Kidney Transplantation / Cyclosporine / Coronavirus Infections / Transplant Recipients / Kidney Failure, Chronic Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Country/Region as subject: Asia Language: English Journal: Am J Transplant Journal subject: Transplantation Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunosuppression Therapy / Kidney Transplantation / Cyclosporine / Coronavirus Infections / Transplant Recipients / Kidney Failure, Chronic Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Country/Region as subject: Asia Language: English Journal: Am J Transplant Journal subject: Transplantation Year: 2020 Document Type: Article