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Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia.
Song, Fengxiang; Shi, Nannan; Shan, Fei; Zhang, Zhiyong; Shen, Jie; Lu, Hongzhou; Ling, Yun; Jiang, Yebin; Shi, Yuxin.
  • Song F; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Shi N; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Shan F; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Zhang Z; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Shen J; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Lu H; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Ling Y; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Jiang Y; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
  • Shi Y; From the Departments of Radiology (F. Song, N.S., F. Shan, Z.Z., J.S., Y.S.) and Infectious Disease (H.L., Y.L.), Shanghai Public Health Clinical Center, No. 2501 Caolang Road, Jinshan District, Shanghai 201508, China; Department of the Principal's Office, Fudan University, Shanghai, China (Z.Z.); C
Radiology ; 295(1): 210-217, 2020 04.
Article in English | MEDLINE | ID: covidwho-13063
ABSTRACT
BackgroundThe chest CT findings of patients with 2019 Novel Coronavirus (2019-nCoV) pneumonia have not previously been described in detail.PurposeTo investigate the clinical, laboratory, and imaging findings of emerging 2019-nCoV pneumonia in humans.Materials and MethodsFifty-one patients (25 men and 26 women; age range 16-76 years) with laboratory-confirmed 2019-nCoV infection by using real-time reverse transcription polymerase chain reaction underwent thin-section CT. The imaging findings, clinical data, and laboratory data were evaluated.ResultsFifty of 51 patients (98%) had a history of contact with individuals from the endemic center in Wuhan, China. Fever (49 of 51, 96%) and cough (24 of 51, 47%) were the most common symptoms. Most patients had a normal white blood cell count (37 of 51, 73%), neutrophil count (44 of 51, 86%), and either normal (17 of 51, 35%) or reduced (33 of 51, 65%) lymphocyte count. CT images showed pure ground-glass opacity (GGO) in 39 of 51 (77%) patients and GGO with reticular and/or interlobular septal thickening in 38 of 51 (75%) patients. GGO with consolidation was present in 30 of 51 (59%) patients, and pure consolidation was present in 28 of 51 (55%) patients. Forty-four of 51 (86%) patients had bilateral lung involvement, while 41 of 51 (80%) involved the posterior part of the lungs and 44 of 51 (86%) were peripheral. There were more consolidated lung lesions in patients 5 days or more from disease onset to CT scan versus 4 days or fewer (431 of 712 lesions vs 129 of 612 lesions; P < .001). Patients older than 50 years had more consolidated lung lesions than did those aged 50 years or younger (212 of 470 vs 198 of 854; P < .001). Follow-up CT in 13 patients showed improvement in seven (54%) patients and progression in four (31%) patients.ConclusionPatients with fever and/or cough and with conspicuous ground-glass opacity lesions in the peripheral and posterior lungs on CT images, combined with normal or decreased white blood cells and a history of epidemic exposure, are highly suspected of having 2019 Novel Coronavirus (2019-nCoV) pneumonia.© RSNA, 2020.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Tomography, X-Ray Computed / Coronavirus Infections / Betacoronavirus / Lung Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Radiology Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Tomography, X-Ray Computed / Coronavirus Infections / Betacoronavirus / Lung Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Radiology Year: 2020 Document Type: Article