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The daily impact of COVID-19 in gastroenterology.
Magro, Fernando; Abreu, Candida; Rahier, Jean-François.
  • Magro F; Department of Biomedicine, University of Porto, Porto, Portugal.
  • Abreu C; Department of Gastroenterology, Centro Hospitalar São João, Porto, Portugal.
  • Rahier JF; MedInUP, Center for Drug Discovery and Innovative Medicines, Porto, Portugal.
United European Gastroenterol J ; 8(5): 520-527, 2020 06.
Article in English | MEDLINE | ID: covidwho-46637
ABSTRACT
A new strain of coronavirus, called SARS-CoV-2, emerged in Wuhan, China, in December 2019, probably originating from a wild-animal contamination. Since then, the situation rapidly evolved from a cluster of patients with pneumonia, to a regional epidemic and now to a pandemic called COrona VIrus Disease 2019 (COVID-19). This evolution is related to the peculiar modes of transmission of the disease and to the globalization and lifestyle of the 21st century that created the perfect scenario for virus spread. Even though research has not evidenced particular susceptibility of inflammatory bowel disease (IBD) patients to SARS-CoV-2 infection, immunosuppressive and immunomodulatory treatments were considered potential risk factors. In this context, initiating treatments with these agents should be cautiously weighted and regular ongoing treatments shall be continued, while the dose of corticosteroids should be reduced whenever possible. Due to the increased risk of contamination, elective endoscopic procedures and surgeries should be postponed and IBD online appointments shall be considered. IBD patients shall also follow the recommendations provided to the general population, such as minimization of contact with infected or suspected patients and to wash hands frequently. In the absence of effective treatments and vaccines, this pandemic can only be controlled through prevention of SARS-CoV-2 transmission with the main objectives of providing patients the best healthcare possible and reduce mortality.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Inflammatory Bowel Diseases / Immunocompromised Host / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Experimental Studies / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: United European Gastroenterol J Year: 2020 Document Type: Article Affiliation country: 2050640620920157

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Inflammatory Bowel Diseases / Immunocompromised Host / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Experimental Studies / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: United European Gastroenterol J Year: 2020 Document Type: Article Affiliation country: 2050640620920157