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Trend of respiratory pathogens during the COVID-19 epidemic.
Sberna, Giuseppe; Amendola, Alessandra; Valli, Maria Beatrice; Carletti, Fabrizio; Capobianchi, Maria Rosaria; Bordi, Licia; Lalle, Eleonora.
  • Sberna G; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
  • Amendola A; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
  • Valli MB; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
  • Carletti F; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
  • Capobianchi MR; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
  • Bordi L; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy. Electronic address: licia.bordi@inmi.it.
  • Lalle E; National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
J Clin Virol ; 129: 104470, 2020 08.
Article in English | MEDLINE | ID: covidwho-478301
ABSTRACT
In Italy, the first SARS-CoV-2 infections were diagnosed in Rome, Lazio region, at the end of January 2020, but sustained transmission occurred later, since the end of February. From 1 February to 12 April 2020, 17,164 nasopharyngeal swabs were tested by real time PCR for the presence of SARS-CoV-2 at the Laboratory of Virology of National Institute for Infectious Diseases "Lazzaro Spallanzani" (INMI) in Rome. In the same period, coincident with the winter peak of influenza and other respiratory illnesses, 847 samples were analyzed by multiplex PCR assay for the presence of common respiratory pathogens. In our study the time trend of SARS-CoV-2 and that of other respiratory pathogens in the same observation period were analysed. Overall, results obtained suggest that the spread of the pandemic SARS-CoV-2 virus did not substantially affect the time trend of other respiratory infections in our region, highlighting no significant difference in rates of SARS-CoV-2 infection in patients with or without other respiratory pathogens. Therefore, in the present scenario of COVID-19 pandemic, differential diagnosis resulting positive for common respiratory pathogen(s) should not exclude testing of SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Orthomyxoviridae / Respiratory Tract Infections / Nasopharynx / Coronavirus Infections / Coronavirus / Influenza, Human Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: J Clin Virol Journal subject: Virology Year: 2020 Document Type: Article Affiliation country: J.jcv.2020.104470

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Orthomyxoviridae / Respiratory Tract Infections / Nasopharynx / Coronavirus Infections / Coronavirus / Influenza, Human Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: J Clin Virol Journal subject: Virology Year: 2020 Document Type: Article Affiliation country: J.jcv.2020.104470