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Prevalence of Asymptomatic SARS-CoV-2 Infection : A Narrative Review.
Oran, Daniel P; Topol, Eric J.
  • Oran DP; Scripps Research Translational Institute, Scripps Research, La Jolla, California (D.P.O., E.J.T.).
  • Topol EJ; Scripps Research Translational Institute, Scripps Research, La Jolla, California (D.P.O., E.J.T.).
Ann Intern Med ; 173(5): 362-367, 2020 09 01.
Article in English | MEDLINE | ID: covidwho-505964
Semantic information from SemMedBD (by NLM)
1. Infected PROCESS_OF Persons
Subject
Infected
Predicate
PROCESS_OF
Object
Persons
2. Asymptomatic PROCESS_OF Persons
Subject
Asymptomatic
Predicate
PROCESS_OF
Object
Persons
3. Congenital anomaly of lung COEXISTS_WITH Asymptomatic Infections
Subject
Congenital anomaly of lung
Predicate
COEXISTS_WITH
Object
Asymptomatic Infections
4. Infected PROCESS_OF Persons
Subject
Infected
Predicate
PROCESS_OF
Object
Persons
5. Asymptomatic PROCESS_OF Persons
Subject
Asymptomatic
Predicate
PROCESS_OF
Object
Persons
6. Congenital anomaly of lung COEXISTS_WITH Asymptomatic Infections
Subject
Congenital anomaly of lung
Predicate
COEXISTS_WITH
Object
Asymptomatic Infections
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world since the first cases of coronavirus disease 2019 (COVID-19) were observed in December 2019 in Wuhan, China. It has been suspected that infected persons who remain asymptomatic play a significant role in the ongoing pandemic, but their relative number and effect have been uncertain. The authors sought to review and synthesize the available evidence on asymptomatic SARS-CoV-2 infection. Asymptomatic persons seem to account for approximately 40% to 45% of SARS-CoV-2 infections, and they can transmit the virus to others for an extended period, perhaps longer than 14 days. Asymptomatic infection may be associated with subclinical lung abnormalities, as detected by computed tomography. Because of the high risk for silent spread by asymptomatic persons, it is imperative that testing programs include those without symptoms. To supplement conventional diagnostic testing, which is constrained by capacity, cost, and its one-off nature, innovative tactics for public health surveillance, such as crowdsourcing digital wearable data and monitoring sewage sludge, might be helpful.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Asymptomatic Diseases Type of study: Prevalence study / Reviews / Risk factors Limits: Humans Language: English Journal: Ann Intern Med Year: 2020 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Asymptomatic Diseases Type of study: Prevalence study / Reviews / Risk factors Limits: Humans Language: English Journal: Ann Intern Med Year: 2020 Document Type: Article