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Quest for a COVID-19 Cure by Repurposing Small Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply
Non-conventional | WHO COVID | ID: covidwho-526153
ABSTRACT
The outbreak of the COVID-19 pandemic has spurred an intense global effort to repurpose existing approved drugs for its treatment. In this review, we highlight the development of seven small molecule drugs that are currently being assessed in clinical trials for the treatment of COVID-19. Three sections are presented for each drug (1) history, mechanism of action, and status of clinical trials;(2) scalable synthetic routes and final forms;and (3) outlook for supply should clinical trials show treatment efficacy. A brief overview of diagnostic testing and vaccine development is also presented.
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Collection: Databases of international organizations Database: WHO COVID Type of study: Diagnostic study / Prognostic study Topics: Vaccines Document Type: Non-conventional

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Collection: Databases of international organizations Database: WHO COVID Type of study: Diagnostic study / Prognostic study Topics: Vaccines Document Type: Non-conventional